临床输血与检验2013，Vol.15Issue(1)：15-18,4.DOI:10.3969/j.issn.1671-2587.2013.01.005
广东籍献血人群HTLV感染状况调查
Survey on HTLV Infection Status for Selected Blood Donors with Natives Cantonese
摘要
Abstract
Objective To understand the prevalence of Human T lymphotropic virus (HTLV) infection among asymptomatic blood population whose birth places were in southeastern coast provinces. Methods Based on their native place, 2 500 blood samples were selectively collected from volunteer donors who were donated their blood and past through the conventional Laboratory tests according to the state standards of blood donation. The samples were then screened by a double antigen sandwich enzyme immunoassay (EIA) against anti-HTLV- Ⅰ / Ⅱ antibodies. After repeated again by EIA, all positive results were performed by Western Blot (WB) as a confirmatory test. Results The primary screening tests obtained five samples of EIA reaction and HTL antibody positive rate reached 0. 20% (5/2 500) . The record revealed that the five blood donors were all native Cantonese. By confirmatory test, only one donor with EIA strong positive (OD = 3. 00) was confirmed to be asymptomatic carrier of HTLV- Ⅰ ,two were indeterminate and another two were negative. The retrospective analysis revealed that this HTLV sero-positive donor had the eligible records as high as six blood donations in our blood center. Conclusion Shenzhen had a low level of HTLV prevalence in blood population. Even if few of blood donors were asymptomatic HTLV carrier, only one repeated donor might have be amplifying several times the potential risk of HTLV transmission through transfusion.关键词
HTLV/血液筛查/无症状携带者/献血人群Key words
HTLV/Blood screening test/Asymptomatic carrier/Blood population分类
医药卫生引用本文复制引用
孙淑君,刘丽华,杨洋,王大明,熊文,叶贤林,孔令魁..广东籍献血人群HTLV感染状况调查[J].临床输血与检验,2013,15(1):15-18,4.基金项目
本课题受深圳市科技计划(No.200702111)资助 （No.200702111）
