临床输血与检验2013，Vol.15Issue(1)：42-44,3.DOI:10.3969/j.issn.1671-2587.2013.01.013
不同方法检测乙肝表面抗原的结果分析
Analysis of the Results of Hepatitis B Surface Antigen Detected by Different Methods
王力达 1马悦 1刘牟林2
作者信息
- 1. 116027 辽宁省大连医科大学附属二院
- 2. 116027 辽宁省大连医科大学检验学院
- 折叠
摘要
Abstract
Objective To analyze the results and the clinical application of HBsAg which was detected by the methods of ELISA and ECLIA. Methods To collect 120 copiesof patients' serum that detected by the method of ELISA . The serum include 30 copies of HBsAg positive serum, 30 copies of HBsAg negative but HBeAb and HBcAb positive serum, 30 copies of HBsAg negative but HBcAb positive serum and 30 copies of Hepatitis B five items detection were all negative serum. To detect the above sera by the method of ELICA, then compare and analyze the test results. Results 30 copies of HBsAg positive serum were all positive after detected by ECLIA ,and the sensitivity rate is 100. 0%. In the 30 copies of HBsAg negative but HBeAb and HBcAb positive serum .there were 4 copies positive after detected by ECLIA ,and the sensitivity rate was 13. 3%. In the 30 copies of HBsAg negative but HBcAb positive and 30 copies of Hepatitis B detection were all negative serum, there were 2 copies positive after detected by ECLIA, the sensitivity rate were both 6.7%. Conclusion The method of ECLIA had higher sensitivity and specificity. It can reflect the HBV infection status of the patients more accurately. It is more suitable for early diagnosis, treatment and curative effect assessment of HBV infection. It has important significance to avoid the infection and dissemination of HBV in the invasive examination, operation and blood transfusion.关键词
乙肝病毒表面抗原/e抗体/核心抗体/酶联免疫吸附法/电化学发光免疫法Key words
HBsAg/HBeAb/HBcAb/ELISA/ECLIA分类
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王力达,马悦,刘牟林..不同方法检测乙肝表面抗原的结果分析[J].临床输血与检验,2013,15(1):42-44,3.
