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双酚A生殖与发育毒性研究现状

任东升 周志俊

环境与职业医学2012,Vol.29Issue(11):722-726,5.
环境与职业医学2012,Vol.29Issue(11):722-726,5.

双酚A生殖与发育毒性研究现状

A Review of Studies on Reproductive and Developmental Toxicities of Bisphenol A

任东升 1周志俊1

作者信息

  • 1. 复旦大学公共卫生学院/教育部公共卫生安全重点实验室,上海200032
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摘要

Abstract

Bisphenol A(BPA) is an well-known environmental endocrine disrupter, with both estrogenic activity and anti-androgenic activity, which is harmful to parents' reproductive system and subsequently to offspring's growth and development. Whether low-dose BPA exposure (below 50 mg/kg/day) can cause adverse effects on reproductive system, brain, and behavior is widely studied in recent years. The reference dose (50 μg/kg/day) established by the United States and the European Union arouses considerable debate. This paper reviewed in vivo experiments and epidemiological studies on BPA to understand the possible adverse health outcomes of BPA exposure.

关键词

双酚A/生殖毒性/发育毒性/神经发育毒性/致癌性

Key words

bisphenol A/ reproductive toxicity/ developmental toxicity/ neuro developmental toxicity/ carcinogenicity

分类

医药卫生

引用本文复制引用

任东升,周志俊..双酚A生殖与发育毒性研究现状[J].环境与职业医学,2012,29(11):722-726,5.

环境与职业医学

OA北大核心CSTPCD

2095-9982

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