环境与职业医学2013，Vol.30Issue(1)：61-62,2.
依地酸钠钙治疗儿童铅中毒的临床疗效观察
Clinical Effectiveness of CaNa2EDTA Treatment in Children with Lead Poisoning
李颖 1肖雄斌 1张晓华 1袁娟1
作者信息
- 1. 湖南省职业病防治院,湖南长沙410007
- 折叠
摘要
Abstract
[ Objective ] To explore the effectiveness and safety of calcium disodium edetate (CaNa2EDTA) intravenous drip administration on childhood chronic lead poisoning. [ Methods ] Sixty children with moderate to severe lead poisoning were admitted to a hospital and treated by CaNa2EDTA intravenous drip administration between 2006 and 2008. Blood lead levels before and after the treatment were recorded and compared. The children were observed for any side effects or abnormality related to the treatment. [ Results ] Of the 60 patients studied, 9 cases had their blood lead level ≥ 700 μg/L, 29 cases in the range of 450-700 μg/L, and 22 cases between 250-449 μg/L. The average blood lead levels before treatment of the 3 blood-lead-level groups were (881.76 ± 141.03)μg/L, (545.47 ± 51.54)μg/L, and (389.07 ± 39.49)μg/L, respectively. After a course of treatment, the average concentrations of blood lead were (585.78 ± 115.17)μg/L, (356.97 ± 27.3)μg/L, and (213.23 ± 37.09)μg/L, respectively. No related abnormality or side effect was observed during the treatment or hospital review. [ Conclusion ] CaNa2EDTA intravenous drip administration has been proved safe and effective in treating children moderate to severe lead poisoning.关键词
儿童/铅中毒/依地酸钠钙Key words
children/ lead poisoning/ calcium disodium edetate分类
医药卫生引用本文复制引用
李颖,肖雄斌,张晓华,袁娟..依地酸钠钙治疗儿童铅中毒的临床疗效观察[J].环境与职业医学,2013,30(1):61-62,2.
