农药学学报2012，Vol.14Issue(6)：607-611,5.DOI:10.3969/j.issn.1008-7303.2012.06.04
4-取代嘧啶基苯磺酰脲类化合物的合成与除草活性
Synthesis and herbicidal activity of novel 4-substituted pyrimidinyl-phenyl-sulfonylureas
摘要
Abstract
Sulfonylurea herbicides, widely applied in agricultural crop protection worldwide, were a milestone of the herbicide development because of its ultra-high activity at low application rates with low toxicity and environmentally benign characteristics. In order to study further structure activity relationship of these kind of herbicides,on the basis of our former studies, 16 novel 4-phenylpyrimidine sulfonylurea compounds were rationally designed and synthesized using monosulfuron and monosulfuron-ester as leads. All structures of the new compounds synthesized were confirmed by 1H NMR,MS and elemental analysis. Preliminary herbicide screening indicated that,most compounds show certain extent inhibitory activity to various weeds at 1.5 kg/hm2,the inhibitory activity to dicotyledonous weeds were better than those to monocotyledonous weeds. Phenyl substituted pyrimidines were not benefit to improvement of herbicide activity.关键词
4-取代苯基嘧啶/磺酰脲/合成/除草活性Key words
4-phenyl-pyrimidine/ sulfonylurea/ synthesis/herbicidal activity分类
化学化工引用本文复制引用
郑占英,陈建宇,刘桂龙,李永红,李正名..4-取代嘧啶基苯磺酰脲类化合物的合成与除草活性[J].农药学学报,2012,14(6):607-611,5.基金项目
国家重点基础研究发展计划("973"计划)项目(2010CB126106课题) （"973"计划）
"十二五"国家科技支撑计划课题(2011BAE06B05)资助. （2011BAE06B05）
