四川医学2012，Vol.33Issue(10)：1816-1818,3.
几种产超广谱β-内酰胺酶细菌耐药性的动态分析
Antimicrobial resistance surveillance study among extend spectrum β-lactamase in different bacterial
邓树琴 1李熙建 1龙琴 1刘影 1谭同均1
作者信息
- 1. 宜宾市第一人民医院检验科,四川宜宾644000
- 折叠
摘要
Abstract
Objective To investigated the detection, distribution and resistance of the commonly extended spectrum be-ta-lactamase producing bacterium in our hospital in 2008 ～2010, and provide the fact for clinical application of antibiotics and infection control. Methods Acquire 1331 strains of pathogenic bacteria witch were isolated in our hospital in the last three years, Vitek-2 compact was used to analyze bacterial identification and susceptibility test, WHONET 5. 5 statistic software was used to analyze the data. Results Among 1331 strains of pathogenic bacteria, 513 strains were extended-spectrum beta-lactamase producing bacterium, accounted for 49. 51%. Urology, Respiratory Medicine, Neonatology and General Surgery were on the top, samples mainly come from respiratory tract, genitourinary tract, purulent secretions. The detection of extended-spectrum beta-lactamase producing bacterium was increasing in the last three years. Susceptibility test results show that the positive strains of ESBL were much lower than the negative strains on drug sensitivity rate. Imipenem, Piperacillin/Tazobactam, Amikacin were high activity. Conclusion The drug resistance of bacterial is increasing currently, especially to extended-spectrum beta-lactamase producing bacterium. Strengthen surveillance of antimicrobial resistance have a positive effect on rational use of antibiotics.关键词
细菌耐药性监测/微生物敏感性试验/β内酰胺酶类Key words
surveillance of antibiotic resistance/ microbial sensitivity tests/ beta-lactamase分类
医药卫生引用本文复制引用
邓树琴,李熙建,龙琴,刘影,谭同均..几种产超广谱β-内酰胺酶细菌耐药性的动态分析[J].四川医学,2012,33(10):1816-1818,3.
