四川医学2012，Vol.33Issue(11)：1941-1943,3.
诺扬复合咪达唑仑在高血压患者全麻拔管期的临床应用观察
Effects of butorphanol combined with midazolam on anesthesia extubation in patients with hypertension
王雄 1华丽 1何斌 1姜敏1
作者信息
- 1. 成都大学附属医院麻醉科,四川成都610081
- 折叠
摘要
Abstract
Objective To observe the prevention effects of combination using of butorphanol and midazolam on anthesia extubation induced cardiovascular and postoperation adverse reaction. Methods 60 patients with primary hypertension were divided into 3 groups at random, controlled group (Ⅰ group) , butorphanol group (Ⅱ group) and butorphanol combined with midazolam group (Ⅲ group) , and used the same method of anesthesia induction and maintenance among 3 groups. Before extubation, the 0. 9% normal saline, butorphanol 0. 02mg/kg and butorphanol 0. 01mg/kg combined with midazolam 0. 02mg/kg were injected respectively for the 3 groups. The parameters of SBP、DBP、HR、SpO2, extubation time and postoperative side effects were recorded. Results The extubation SBP、DBP、HR、SpO2 of group Ⅱ and group Ⅲ were keeping more stable than group Ⅰ( P <0.05). The number of patients with nausea and vomiting, resdessness in group 1 was more than other 2 groups. Extubation time between group 1 and II were not statistically significant but all shorter than group III( P <0. 05). Conclusion using of butorphanol and midazolam in patients with hypertension can effectively prevent tracheal extubation induced cardiovascular response and with less adverse reactions.关键词
酒石酸布托啡诺/咪达唑仑/气管拔管期/心血管不良反应Key words
butorphanol tartrate/ midazolam/ tracheal extubation/ cardiovascular adverse reactions分类
医药卫生引用本文复制引用
王雄,华丽,何斌,姜敏..诺扬复合咪达唑仑在高血压患者全麻拔管期的临床应用观察[J].四川医学,2012,33(11):1941-1943,3.
