四川医学2012，Vol.33Issue(12)：2201-2204,4.
去游离甘油三酰甘油对Friedewald公式计算低密度脂蛋白胆固醇的影响
To investigate the impact of triglyceride freed glycerol for low density lipoprotein cholesterol concentration calculated by Friedewald formula
刘运双 1曾平 1陈曦1
作者信息
- 1. 绵阳市中心医院检验科,四川绵阳621000
- 折叠
摘要
Abstract
Objective To evaluate the impact of triglyceride freed glycerol for low density lipoprotein cholesterol concentration calculated by Friedewald formula. Methods Serum total cholesterol (TC) , triglyceride (TG) , high density lipoprolen cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) concentrations were measured in 5302 patients, TG were measured by glycerol-blanked assay. A total 5016 patients with TG concentrations ≤4. 51mmol/l were enrolled, the LDL-C concentrations were also calculated by Friedewald formula. Comparison of LDL-C concentrations calculated by the Friedewald formula (LDL-C(F)) and measured by direct homogeneous (LDL-C(M)) assay were performed. The concordances of the National Cholesterol Education Program (NCEP) risk category were estimated. Results Both in normal and moderate high and high TG group, LDL-C ( F) correlated with LDL-C (M): γ = 0. 880, 0. 943,and 0. 897 respectively. The mean concentrations of LDL-C (F) were significantly higher than those of LDL-C (M) in normal and moderate high and high TG group. The average of concordance for NCEP categories were 77.4%. Conclusion The concentrations of LDL-C (F) were significantly higher than those of LDL-C ( M ) , when freed glycerol assay were used for measuring TG.关键词
甘油/三酰甘油/Friedewald公式/低密度脂蛋白胆固醇Key words
glycerol/ triglyderide/ Friedewald formula/ low density lipoprotein cholesterol分类
医药卫生引用本文复制引用
刘运双,曾平,陈曦..去游离甘油三酰甘油对Friedewald公式计算低密度脂蛋白胆固醇的影响[J].四川医学,2012,33(12):2201-2204,4.
