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结核感染T细胞斑点试验在结核诊断中的应用

王永生 刘蔺 周航 宁靓 徐小雅

四川医学2013,Vol.34Issue(1):10-12,3.
四川医学2013,Vol.34Issue(1):10-12,3.

结核感染T细胞斑点试验在结核诊断中的应用

Diagnositic value of interferon-gamma release assay T.Spo+TB for tuberculosis: a prospectiv cohort study.

王永生 1刘蔺 1周航 1宁靓 1徐小雅1

作者信息

  • 1. 成都363医院呼吸科,四川,成都,610041
  • 折叠

摘要

Abstract

Objective To compare the sensitivity and speficity in diagnosis of tuberculosis by interferon-gamma release assy(T-Spot. TB) to the tuberculosis skin test(TST) , in order to discuss their diagnositic values. Methods 68 patients suspected to be infected with tuberculosis were taken into study. They were individually tested by T-Spot. TB and Tuberculosis Skin Test. When their diagnosis were certain, the sensitivity, speficity, positive prospective value, negative prospective value, positive likelihood ratio and negative prospective ratio of the two different diagnosis method were calculated. Results Ultimatidely 48 patients were confirmed to have tuberculosis infected. The T-Spot. TB apperanced abvious advantages in sensitivity, speficity, posi tive prospective value, negative prospective value, positive likelihood ratio compared to TST. Conclusion The T-Spot. TB is a quicker and more sensitive method in the diagnosis of tuberculosis compared to TST. It is valueable and applicable as a screening test.

关键词

结核/结核感染T细胞斑点试验/结核菌素试验

Key words

tuberculosis/interferon-gamma release assy/T. Spot TB/tuberculosis skin test

分类

医药卫生

引用本文复制引用

王永生,刘蔺,周航,宁靓,徐小雅..结核感染T细胞斑点试验在结核诊断中的应用[J].四川医学,2013,34(1):10-12,3.

基金项目

四川省卫生厅科研课题(编号:100358) (编号:100358)

四川医学

OACSTPCD

1004-0501

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