四川中医2013，Vol.31Issue(2)：55-57,3.
温补脾肾法对脾肾阳虚型甲状腺功能减退症大鼠肾脏抗氧化能力的影响
Effect of Tonifying Spleen-kidney Method on Kidney Antioxidative Capability of Spleen-kidney Yang Deficiency Hypothyroid Rats
张云芬 1房辉 2马青松 1郭咏莉1
作者信息
- 1. 迁安市中医医院内分泌科,河北迁安064400
- 2. 唐山工人医院内分泌科,河北唐山063000
- 折叠
摘要
Abstract
Objective: To study the effect of tonifying spleen-kidney method on kidney antioxidative capability of spleen-kidney Yang deficiency hypothyroid rats, and then exploring its mechanism. Methods; 30 Wistar rats, male and female in half, were randomly divided into 3 groups (n= 10) , namely the control group (control) , hypothyroidism (HT) , and tonifying group (WB). Spleen-kidney Yang deficiency hypothyroid rat model was induced by intragastric administration of Methimazole, killed the rats after treatment of tonifying Spleen-kidney recipe for 4 weeks. Measuring the contents of GSH-PX, SOD, MDA in kidney issue. Results: Compared with model group, the levels of SOD was increased (P＜0. 01), GSH-PX and MDA was decreased (P＜0. 01 or P＜0. 05) in WB group of renal tissue. There was no significant differences (P＞ 0. 05) between WB group and control group. Conclusions; Tonifying spleen-kidney method can increase kidney antioxidative capability of spleen-kidney Yang deficiency hypothyroid rats.关键词
甲减肾脏/温补脾肾/抗氧化能力/脾肾阳虚Key words
Kidney in hypothyroid state/ Tonifying spleen-kidney method/ Antiperoxidation ability/ Spleen-kidney Yang deficiency分类
医药卫生引用本文复制引用
张云芬,房辉,马青松,郭咏莉..温补脾肾法对脾肾阳虚型甲状腺功能减退症大鼠肾脏抗氧化能力的影响[J].四川中医,2013,31(2):55-57,3.
