生物医学工程研究2012，Vol.31Issue(4)：268-270,3.
氩氦刀治疗原发性肝癌对机体特异性T细胞免疫的影响
Effect of T Cellular Immunity Activation after Cryosurgery in Primary Liver Cancer Patients
摘要
Abstract
To study the activate effect of T lymphocyte immunity after cryosurgery in primary liver eancer(PLC) patients. Twelve patients diagnosed PLC by puncture biopsy, the tumor tissue was prepared for tumor antigen. With the guidance of CT or ultrasonic image, the tumor was ablated by cryosurgery. The AFP lever was detected by Radioimmunoassay, activation of cytotoxic T lymphocytes were investigated by ELJSPOT. Combined with the baseline, after cryosurgery, the AFP lever increased temporally, and then decreased to a lower lever. Tumor antigen specific - cytotoxic T lymphocytes were activated effectively (P <0.01). Cryosurgery can effectively activate tumor antigen - specific T lymphocytes, tumor derived antigen can induce specific T lymphocytes.关键词
原发性肝癌/氩氦刀/T细胞免疫Key words
Primary liver carcinoma/ Cryosurgery/T cell immunity分类
医药卫生引用本文复制引用
骆益宙,钱维源,张海涛,黄璜,赵青,廖辉..氩氦刀治疗原发性肝癌对机体特异性T细胞免疫的影响[J].生物医学工程研究,2012,31(4):268-270,3.基金项目
南京军区医药卫生科研项目(10MA56) （10MA56）
中国医师协会课题(20120112). （20120112）
