山东医药2012,Vol.52Issue(44):8-10,3.
新疆哈萨克族高血压病与胰岛素抵抗及影响因素分析
Investigation of the relationship between hypertension and insulin resistance and analysis of relative influential factors in Xinjiang Kazak
摘要
Abstract
Objective To investigate the relationship between hypertension and insulin resistance and analysis of relative influential factors in Xinjiang Kazak. Methods A total of 177 Kazak adults were collected. Body mass index ( BMI) , blood pressure, waist/hip ratio (WHR) , the triglyceride (TG) , the total cholesterol (TC), the low-density lipoprotein (LDL) , the high-density lipoprotein (HDL) , fasting glucose ( FBG) and fasting insulin (FINS) were measured in all cases. Homeostasis model assessment of insulin resistance (HOMA-IR) and insulin sensitive index (ISI) were used to assess insulin resistance. According to the level of blood pressure, those people were divided into normal group and hypertensive group. Results The level of insulin resistance index of Kazak hypertensive group was significantly higher than the normal group, and the level of ISI of Kazak hypertensive group was significantly lower than the normal group ( P < 0. 05 ). Levels of systolic blood pressure, diastolic blood pressure were positively correlated with HOMA-IR between Kazak hypertension patients (P <0. 01). Multiple regression analysis showed that BMI and TG were independent determinants for HOMA-IR. Conclusion There is a close relationship between hypertension and insulin resistance in Xinjiang Kazak.关键词
高血压/胰岛素抵抗/胰岛素抵抗指数/胰岛素敏感指数Key words
hypertension/ insulin resistance/ insulin resistance index/ insulin sensitive index分类
医药卫生引用本文复制引用
李娜,王丽,程江,丁虎,王忠,汪道文,徐宇军,张望强,段军仓..新疆哈萨克族高血压病与胰岛素抵抗及影响因素分析[J].山东医药,2012,52(44):8-10,3.基金项目
国家自然科学基金—地区科学基金项目(30760216). (30760216)