山东医药2012，Vol.52Issue(46)：28-31,4.
磁共振DTI与DTT在星形细胞瘤分级诊断中的应用价值
Application value of DTI and DTT in diagnosis of different grades astrocytoma
魏璇 1金国宏 2哈若水1
作者信息
- 1. 宁夏人民医院,银川750002
- 2. 宁夏医科大学总医院
- 折叠
摘要
Abstract
Objective To measure and analysis ADC and FA of the high-grade and low-grade intracranial astrocytoma, to discuss the values of DTI and diffusion tensor tractography ( DTT) in the diagnosis of different grades astrocytoma. Methods A total of 30 cases astrocytoma were performed by pathology (including 14 cases of WHO Ⅰ -Ⅱ ,16 cases of WHO Ⅲ-Ⅳ). Average ADC and FA values were measured in the tumor parenchyma region, peri-tumoral region (with a distant of 1. 5 cm which outside the tumor parenchyma region) and corresponding contralateral normal brain tissue. The impact of morphology and struction about white matter fiber bundle was observed in the different grades astrocytoma. Results Signal intensity of 30 cases astrocytoma about ADC and FA maps in tumor parenchyma region, peri-tumoral region and normal brain tissue were obviously different. FA and ADC values of tumor parenchyma and peri-tumoral region were obviously lower than normal brain tissue. On FA and DTT map of Ⅰ and Ⅱ grade astrocytoma, the white matter fiber bundle mainly showed significant rarefaction and displacement of fiber bundles, with clear boundary adjacent to the white matter. Whereas invasion and infiltration of the white matter fiber bundles with relatively ill-defined border were showed in Ⅲ and Ⅳgrade astrocytoma. On DTT map of Ⅲ-Ⅳgrade astrocytoma,showd partial disruption, compression, deviation and displacement fiber bundles. Compared with the contralateral normal brain tissue, FA values of tumor parenchyma and peri-tumoral region were obvious lower( P < 0. 05 ) . ADC values of Ⅲ and Ⅳgrade astrocytoma in tumor parenchyma region were obvious lower than Ⅰ and Ⅱ grade astrocytoma ( P < 0. 05 ). There were similar ADC values of peri-tumoral region between Ⅰ -Ⅱ and v-Ⅳ grade astrocytoma, which were not obvious significant differences ( P >0.05). Conclusions DTI can help define different grades astrocytoma and can distinguish tumor parenchyma between peri-tumoral region. DTT can clearly show the destructive degree of cerebral white matter fiber bundle in different grades astrocytoma.关键词
磁共振扩散张量成像/脑白质纤维束成像/神经胶质瘤Key words
magnetic resonance diffusion tensor imaging/ cerebral white matter fiber bundle imaging/ glioma分类
医药卫生引用本文复制引用
魏璇,金国宏,哈若水..磁共振DTI与DTT在星形细胞瘤分级诊断中的应用价值[J].山东医药,2012,52(46):28-31,4.
