丝绸2012，Vol.49Issue(11)：1-5,5.
丝胶蛋白的细胞相容性和抗菌性能研究
Cytocompatibility and antibacterial properties of sericin proteins
摘要
Abstract
This paper studies the cytocompatibility of sericin proteins (S1, S2) extracted from cocoon shell and cocoon outer floss respectively and small molecule sericin protein peptide (S3) prepared by enzymolysis of cocoon shell sericin, and studies the antibacterial properties against Gram-negative bacteria and Gram-positive bacteria. Results show that: all these three kinds of sericin protein have not toxicity to cells, and show the function of promoting cell growth with the increase of sericin concentration. Have a quantitative test of bacterial inhibition rate of sericin under each concentration gradient by using bacterial growth inhibition test, and results show that sericin has significant antibacterial properties, and inhibition rates of Staphylococcus aureus and Escherichia coli in descending order are S3, S1, S2 and S2, S3, S1 respectively, and sericin concentration has effects on their antibacterial properties. The results suggest that sericin is a kind of biocompatible material with good antibacterial properties.关键词
丝胶蛋白/细胞相容性/抗菌性Key words
Sericin proteins/ Cytocompatibility/ Antibacterial properties分类
轻工纺织引用本文复制引用
陈忠敏,罗琴,张瑶琴,刘琼..丝胶蛋白的细胞相容性和抗菌性能研究[J].丝绸,2012,49(11):1-5,5.基金项目
重庆市高等学校优秀人才支持计划项目(2011CQ04) （2011CQ04）
重庆理工大学研究生创新基金项目(YCX2011310) （YCX2011310）
