世界中医药2013，Vol.8Issue(1)：74-75,2.DOI:10.3969/j.issn.1673-7202.2013.01.030
化瘀中药加核糖核酸在治疗小鼠溃疡性结肠炎中对TNF-α的影响
Effect of Stasis Removing Herbs plus RNA-based Drugs on TNF- alpha in Mice with Ulcerative Colitis
摘要
Abstract
Objective: To observe the effect of stasis removing herbs plus RNA-based drugs on TNF- alpha in mice with ulcerative colitis ( UC ). Methods:A total of 42 mice with UC, female or masculinity were chosen and divided into three groups, control group, stasis removing herbs plus RNA-based drugs group and norfloxacin group. After eight-day observation and treatment, we measured the changes of TNF-α. Results: The stasis removing herbs plus RNA-based drugs group presented obvious therapeutic effect. The level of TNF-ct reduces to the normal level ( P <0. 01 ). Conclusion: Stasis removing herbs plus RNA-based drugs have obvious therapeutic effect on UC, and one of its mechanisms is to reduce the level of TNF-α.关键词
溃疡性结肠炎/肿瘤坏死因子/化瘀药/核糖核酸Key words
UC/ TNF-ct/ Stasis removing herbs/ RNA引用本文复制引用
宋明福,刘敏..化瘀中药加核糖核酸在治疗小鼠溃疡性结肠炎中对TNF-α的影响[J].世界中医药,2013,8(1):74-75,2.基金项目
湖北省重点科技发展项目立项课题(编号:2001AA309B04) （编号:2001AA309B04）
