现代检验医学杂志2012，Vol.27Issue(6)：139-141,3.DOI:10.3969/j.issn.1671-7414.2012.06.045
卵泡液中VEGF水平对体外受精-胚胎移植临床结局的影响
Effect of Vascular Endothelial Growth Factorin Follicle Fluid on ART
王振荣 1田喜凤1
作者信息
- 1. 河北联合大学生命科学学院,河北唐山,063000
- 折叠
摘要
Abstract
Objective To study the relationship between the level of vascular endothelial growth factor (VEGF) and the outcomes of pregnancy in infertility patients undergoing IVF-embryo transfer (IVF-ET) treatment. Methods 95 cases of female patients undergoing IVF treatment cycle were selected from July 2011 to January 2012. The enzyme-linked immunosor-bent assay (ELISA) were used to detect VEGF levels of COH Day puncture specimens in the follicular fluid, and corresponding eggmaturity and subsequent embryo quality were timely recorded and the outcome of pregnancy were observed follow-up. Results VEGF concentration (2 395. 1 ± 218. 6 pg/ml) of the follicular fluid in mature eggs was significantly higher than that of the immature oocytes (1 569.4 ± 166.2 pg/ml),the difference was statistically significant (t=14.120,P< 0. 05) ;the VEGF levels (3 236. 7 ± 245. 2 pg/ml) of follicular fluid in the quality embryonic group was higher than that of the non-quality embryo group (2 989. 3 v 258. 1 pg/ml) , the difference was statistically significant (t= 3. 400, P<0. 05). The VEGF levels (4 693. 1 ± 326. 4 pg/ml) of follicle fluid in the pregnancy was higher than that of the non-pregnant group (2 666.6 ± 233.9 pg/ml),the difference was statistically significant (t= 26. 118, P<0. 05). Conclusion The outcome of IVF-ET might be predicted by detecting the levels of VEGF in follicular fluid.关键词
卵泡液/血管内皮生长因子(VEGF)/体外受精-胚胎移植(IVF-ET)Key words
follicular fluids/ vascular endothelial growth factor(VEGF) /in vitro fertilization and embryo transfer(IVF-ET)分类
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王振荣,田喜凤..卵泡液中VEGF水平对体外受精-胚胎移植临床结局的影响[J].现代检验医学杂志,2012,27(6):139-141,3.
