实用妇产科杂志2012，Vol.28Issue(12)：1042-1044,3.
甲氨蝶呤联合米非司酮治疗异位妊娠的临床观察
The Application of Methotrexate Combined with Mifepristone in the Treatment of Ectopic Pregnancy
何静 1杨洋 1李华丽1
作者信息
- 1. 西安医学院附属医院,陕西西安710077
- 折叠
摘要
Abstract
Objective:To evaluate the efficacy of methotrexate combined with mifepristone in the treatment of ectopic pregnancy, and to explore new conservative treatment alternatives for ectopic pregnancy. Methods:70 cases of patients diagnosed as ectopic pregnancy in our hospital from January 2010 to December 2011 were randomly divided into two groups, the methotrexate group (control), and the methotrexate combined with mifepristone group (experimental). Results:In both groups,after 2 weeks treatment,the serum HCG level decreased significantly, and the mass average diameter significantly reduced too (P < 0. 05 and P<0. 01,respectively). The success rate of methotrexate (control) group and the methotrexate combined with mifepristone group (experimental) were 91.67% and 76.47% respectively,and the difference was significant. Conclusions:The treatment effect in the methotrexate combined with mifepristone group is better than that of methotrexate group. And there are other advantages,such as higher effective rate,lower side effects, shorter duration of therapy, and significantly reducing the economic burden of the patients. Therefore,the methotrexate combined with mifepristone treatment method is a good method to be explored.关键词
甲氨蝶呤/米非司酮/异位妊娠Key words
Mifepristone/ Methotrexate/Ectopic pregnancy分类
医药卫生引用本文复制引用
何静,杨洋,李华丽..甲氨蝶呤联合米非司酮治疗异位妊娠的临床观察[J].实用妇产科杂志,2012,28(12):1042-1044,3.
