实用医学杂志2012，Vol.28Issue(9)：1452-1454,3.DOI:10.3969/j.issn.1006-5725.2012.09.022
冠状动脉慢血流患者外周血内皮祖细胞数量的变化
Changes of circulating endothelial progenitor cells in patients with coronary slow flow
摘要
Abstract
Objective To observe the changes of circulating endothelial progenitor cells (EPCs) in patients with coronary slow flow (CSF). Methods Twenty-six CSF patients (G1 group) and 20 normal controls (G2 group) were selected in this study. CSF was diagnosed when the corrected TIMI frame count (CTFC) was more than 27 frames, Peripheral blood samples were drawn to isolate and culture EPCs, respectively. EPCs populations were assessed by the colony forming unit assay (EPC-CFU) through an inverted phase contrast microscope after 10 days of culturing. Results There were no significant differences in age, sex, smoking history, hypertension, diabetes mellitus, family history of coronary heart disease, and blood lipid between the tow groups (P 〉 0.05) ; the level of circulating EPCs in G1 group was lower than that in G2 group (11.3 ± 2.9 vs. 17.1 ±2.4, P 〈 0.05). Conclusion Circulating EPCs populations are lower in CSF patients.关键词
冠状动脉疾病/冠状血管造影术/血流速度/内皮祖细胞Key words
Coronary artery disease/ Coronary angiography/ Blood flow velocity/ Endothelial progenitor cells引用本文复制引用
范磊,张金盈,张力,赵江涛,张梦瑶..冠状动脉慢血流患者外周血内皮祖细胞数量的变化[J].实用医学杂志,2012,28(9):1452-1454,3.基金项目
河南省科技创新人才基金资助项目(编号:094100510017) （编号:094100510017）
