实用医学杂志2012，Vol.28Issue(10)：1701-1703,3.DOI:10.3969/j.issn.1006-5725.2012.10.049
盐酸米多君及美托洛尔治疗儿童体位性心动过速综合征的对比研究
Comparison of the efficacies of metoprolol and midodrine hydrochloride in treating children with postural orthostatic tachycardia syndrome
摘要
Abstract
Objective To evaluate the efficacies of different therapeutic methods in treating children with postural orthostatic tachycardia syndrome (POTS). Methods 92 children with POTS were randomly divided into normal saline group (administered with normal saline), midodrine hydrochloride group (administered with normal saline and midodrine hydrochloride),and metoprolol group (administered with normal saline and metoprolol). Symptom score, the effective rates, and hemodynamic changes of head-up tilt test (HUT) 2 months after therapy were compared among the three groups. Results Symptom score in midodrine hydrochloride group and metoprolol group were much lower than that in normal group (P < 0.05), but there was no significant difference between midodrine hydrochloride group and metoprolol group (P > 0.05). Difference of heart beating rates, vertical heart rate, and the effective rates in metoprolol group were better than those in midodrine hydrochloride group (P < 0.05), in which those were better than those in normal saline group (P < 0.05). Conclusions Both midodrine hydrochloride and metoprolol could ameliorate clinical symptoms and improve clinical effects in children with POTS, especially metoprolol.
关键词
心动过速/美托洛尔/盐酸米多君Key words
Tachycardia/Metoprolol/Midodrine hydrochloride引用本文复制引用
孙微微..盐酸米多君及美托洛尔治疗儿童体位性心动过速综合征的对比研究[J].实用医学杂志,2012,28(10):1701-1703,3.
