实用医学杂志2012，Vol.28Issue(23)：3877-3880,4.DOI:10.3969/j.issn.1006-5725.2012.23.009
冠心病患者血浆白介素-35水平与左室射血分数相关性分析
Correlation between plasma IL-35 and left ventricular ejection fraction in patients with coronary artery diseases
摘要
Abstract
Objective To investigate the relationship between plasma IL-35 and left ventricular ejection fraction (LVEF) in patients with coronary artery diseases (CAD). Methods 98 patients with CAD were divided into 3 groups: stable angina (SA) group (n = 30), unstable CAD (UA) group (n = 40) and acute myocardial infarction (AMI) group (n = 28). 33 cases with normal angiographic results were included as control group. The plasma levels of IL-35 were measured by ELISA, and LVEF was quantified by the Biplane Simpson's method in 2-dimensionnal echocardiography. Results The plasma levels of IL-35 in patients with CAD were significantly lower than that in control group, and those in UA group and AMI group were lower than that in SA group. As compared to that in control group, the LVEF was lower in SA group and AMI group. Plasma level of IL-35 was positively correlated with LVEF in patients with CAD. Conclusion The plasma level of IL-35 may be related to the pathogenesis and prognosis of CAD.关键词
冠心病/IL-35/左室射血分数Key words
Coronary disease/ IL-35/ Left ventricular ejection fraction引用本文复制引用
黄瑛,施莹,林英忠,罗程,陆政德,刘伶,王小燕,林盛源,吉庆伟..冠心病患者血浆白介素-35水平与左室射血分数相关性分析[J].实用医学杂志,2012,28(23):3877-3880,4.基金项目
国家自然科学基金资助项目(编号:81160045) （编号:81160045）
