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还原型谷胱甘肽对急性一氧化碳中毒患者心肌的保护作用

施卫东 项文坤 吴新开

实用医学杂志2012,Vol.28Issue(23):3983-3985,3.
实用医学杂志2012,Vol.28Issue(23):3983-3985,3.DOI:10.3969/j.issn.1006-5725.2012.23.052

还原型谷胱甘肽对急性一氧化碳中毒患者心肌的保护作用

Protective effect of reduced glutathione on myocardial damage in patients with acute carbon monoxide poisoning

施卫东 1项文坤 1吴新开1

作者信息

  • 1. 333200,江西省婺源县人民医院
  • 折叠

摘要

Abstract

Objective To study the protective effect of reduced glutathione (GSH) on myocardial damage in patients with acute carbon monoxide poisoning (ACMP). Methods 93 patients with myocardial damage induced by ACMP were divided into treatment group (n = 52) and control group (n = 41). Conventional treatment was given to both groups, and the treatment group was treated with 1 800 mg of GSH once a day, additionally. The changes of myocardial enzyme spectrum (CK-MB) and cardiac troponin I (cTnI) were analyzed. Results CK-MB as well as cTnI were all improved significantly in the treatment group, and the changes were superior to those in the control group (P 〈 0.05). Conclusion GSH has the protective effect on myocardial damage induced by ACMP.

关键词

一氧化碳中毒/肌酸激酶同工酶/肌钙蛋白I/还原型谷胱甘肽

Key words

Carbon monoxide poisoning/ CK-MB/ cTnI/ Reduced glutathione

引用本文复制引用

施卫东,项文坤,吴新开..还原型谷胱甘肽对急性一氧化碳中毒患者心肌的保护作用[J].实用医学杂志,2012,28(23):3983-3985,3.

实用医学杂志

OA北大核心CSTPCD

1006-5725

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