实用肿瘤杂志2013，Vol.28Issue(1)：68-70,3.
紫杉醇联合卡培他滨治疗复发转移性胃癌临床疗效分析
Efficacy of paclitaxel combined with capecitabine in treatment of advanced gastric cancer
常顺伍1
作者信息
- 1. 海南省人民医院普通外科,海南海口570100
- 折叠
摘要
Abstract
Objective To investigate the clinical effect and side effects of paclitaxel combined with eapecitabine in the treatment for patients with advanced gastric cancer. Methods Twenty patients with advanced gastric cancer recurrence after chemotherapy were treated with the combination of paclitaxel and eapecitabine. The patients were administrated with oral eapecitabine (1 000 mg/m2 ,bid, d 1 - 14) and intravenous paclitaxel (135 mg/m2 ,d 1, d 8) in a 21-day cycle regimen. Results A total of 5 cases showed PR (25. 0% ) , 12 SD (60.0% ) and 3 PD (15.0% ). Meanwhile,the response rate (RR) was 25.0% and the disease control rate (DCR) was 85.0%. The median remission time and the median survival time were 5 months and 12 months,respectively. The main side effects were myelosuppression and hand-foot syndrome. The degree of these side reactions were only Ⅰ or Ⅱ level. Conclusion The combination of paclitaxel and eapecitabine is effective and well-tolerated in the treatment of advanced gastric cancer recurrence after chemotherapy.关键词
胃肿瘤/药物疗法/紫杉醇/治疗应用/卡培他滨/治疗应用/生活质量Key words
stomach neoplasms/drug therapy/ paclitaxel/therapeutic use/ eapecitabine/therapeutic use/ quality of life分类
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常顺伍..紫杉醇联合卡培他滨治疗复发转移性胃癌临床疗效分析[J].实用肿瘤杂志,2013,28(1):68-70,3.
