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超声辐射力弹性成像系统研究及仿体实验

陈昕 郭燕荣 王毅 沈圆圆 林浩铭 朱颖 郑翊 汪天富 陈思平

深圳大学学报(理工版)2013,Vol.30Issue(1):54-59,6.
深圳大学学报(理工版)2013,Vol.30Issue(1):54-59,6.DOI:10.3724/SP.J.1249.2013.01054

超声辐射力弹性成像系统研究及仿体实验

Ultrasonic radiation force elastography system for measuring tissue viscoelasticity: an in vitro study on phantom and rat liver

陈昕 1郭燕荣 1王毅 1沈圆圆 1林浩铭 1朱颖 1郑翊 2汪天富 1陈思平1

作者信息

  • 1. 医学超声关键技术国家地方联合工程实验室,广东省生物医学信息检测与超声成像重点实验室,深圳大学医学院,深圳518060
  • 2. 美国圣克劳德州立大学电子与计算机工程系,圣克劳德56301,美国
  • 折叠

摘要

Abstract

The system of ultrasonic radiation force elastography mainly consists of excitation component and detection component. The excitation transducer was focused on one location within the medium to generate harmonic vibration and shear wave propagation, and the detection transducer was applied to detect the shear wave at other locations along the propagation path of shear wave using pulse-echo method. The received echoes were amplified, filtered, digitized and then processed by Kalman filter to estimate the vibration phase. According to the phase changes between different propagation locations, the shear wave speeds were estimated, and ultimately, tissue elasticity and viscosity moduli were calculated. Preliminary studies on agar phantom and in vitro healthy rat liver verify the operability and measurement accuracy of the entire system. The results show that the system can effectively measure the viscoelasticity of phantom and rat liver, which will provide good support for our subsequent studies.

关键词

超声学/辐射力弹性成像/剪切波/卡尔曼滤波/黏弹性/医学图像

Key words

ultrasonics/ radiation force elastography/ shear waves/ Kalman filter/ viscoelasticity/ medical image

分类

医药卫生

引用本文复制引用

陈昕,郭燕荣,王毅,沈圆圆,林浩铭,朱颖,郑翊,汪天富,陈思平..超声辐射力弹性成像系统研究及仿体实验[J].深圳大学学报(理工版),2013,30(1):54-59,6.

基金项目

国家自然科学基金资助项目(61031003,81271651) (61031003,81271651)

深圳大学学报(理工版)

OA北大核心CSTPCD

1000-2618

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