深圳大学学报(理工版)2013,Vol.30Issue(1):54-59,6.DOI:10.3724/SP.J.1249.2013.01054
超声辐射力弹性成像系统研究及仿体实验
Ultrasonic radiation force elastography system for measuring tissue viscoelasticity: an in vitro study on phantom and rat liver
摘要
Abstract
The system of ultrasonic radiation force elastography mainly consists of excitation component and detection component. The excitation transducer was focused on one location within the medium to generate harmonic vibration and shear wave propagation, and the detection transducer was applied to detect the shear wave at other locations along the propagation path of shear wave using pulse-echo method. The received echoes were amplified, filtered, digitized and then processed by Kalman filter to estimate the vibration phase. According to the phase changes between different propagation locations, the shear wave speeds were estimated, and ultimately, tissue elasticity and viscosity moduli were calculated. Preliminary studies on agar phantom and in vitro healthy rat liver verify the operability and measurement accuracy of the entire system. The results show that the system can effectively measure the viscoelasticity of phantom and rat liver, which will provide good support for our subsequent studies.关键词
超声学/辐射力弹性成像/剪切波/卡尔曼滤波/黏弹性/医学图像Key words
ultrasonics/ radiation force elastography/ shear waves/ Kalman filter/ viscoelasticity/ medical image分类
医药卫生引用本文复制引用
陈昕,郭燕荣,王毅,沈圆圆,林浩铭,朱颖,郑翊,汪天富,陈思平..超声辐射力弹性成像系统研究及仿体实验[J].深圳大学学报(理工版),2013,30(1):54-59,6.基金项目
国家自然科学基金资助项目(61031003,81271651) (61031003,81271651)