生殖医学杂志2012，Vol.21Issue(z1)：36-41,6.DOI:10.3969/j.issn.1004-3845.2012.z1.007
Relationship between lower number of oocytes retrieved and clinical outcomes of in vitro fertilization-embryo transfer
Relationship between lower number of oocytes retrieved and clinical outcomes of in vitro fertilization-embryo transfer
Wang Xue-mei 1Jiang Hong 2Zhang Wen-xiang 2Wei Zhao-lian3
作者信息
- 1. Reproductive Medicine Center, Clinical College of PLA, Anhui Medical University, Hefei 230031
- 2. Reproductive Medicine Center,the 105th Hospital of PLA, Hefei 230031
- 3. Department of Reproductive Medicine Center, Obstetrics & Gynecology Department, the First Affiliated Hospital of Anhui Medical University, Hefei 230022
- 折叠
摘要
Abstract
Objective: To explore the clinical outcomes of the infertile women with retrieved oocytes less than or equal to 5 undergoing in vitro fertilization-embryo transfer (IVF-ET) or intracytoplasmic sperm injection (ICSI).Methods: The clinical data of 216 embryo transfer cycles with retrieved oocytes less than or equal to 5 during the procedure of IVF/ICSI in Reproductive Medicine Center of the 105th Hospital of PLA from Jul.2008 to Dec.2011 were analyze retrospectively.All the patients were divided into group A (＜ 35 years),group B (35-39 years) and group C (≥40 years) according to the ages,and 409 IVF/ICSI cycles with patients’ age less than 35 years old and 6-15 retrieved oocytes in the same period were served as controlled group.Then the patients ≥ 35 years were subdivided into gonadotropin-releasing hormone agonist (GnRH-a) long protocol group,GnRH-a short group and GnRH antagonist group according to the protocols of controlled ovarian hyperstimulation (COH).The clinical date and the outcomes were analyzed and compared among all groups.Results: There were significantly differences in clinical pregnancy rate (38.3 ％ vs.19.4 ％) and early abortion rate (16.1％ vs.50.0％) between group A and group C (P＜0.05),and there were no significant differences in clinical pregnancy rate(38.3％ vs.41.6％)and early abortion rate (16.1％ vs.10.0％) between group A and control group (P＞0.05).There were no significant differences in clinical pregnancy rates (29.01％ vs.26.1％ vs.25.9％)and early abortion rates (33.3％ vs.33.3％ vs.40.0％) among GnRH-a long protocol group,GnRH-a short group and GnRH antagonist group (P＞0.05).Conclusions: Relatively satisfactory clinical outcomes of IVF/ICSI would still be got for the patients ＜35 years with retrieved oocytes less than or equal to 5,but whatever COH protocols such as GnRH-a long protocol,GnRH-a short and GnRH antagonist could not improve the outcomes of IVF/ICSI for the patients aged ≥35 with retrieved oocytes less than or equal to 5.关键词
In vitro fertilization-embryo transfer/ Age/ Controlled ovarian hyperstimulation/ Number of retrieved oocytes/ Clinical outcomesKey words
In vitro fertilization-embryo transfer/ Age/ Controlled ovarian hyperstimulation/ Number of retrieved oocytes/ Clinical outcomes引用本文复制引用
Wang Xue-mei,Jiang Hong,Zhang Wen-xiang,Wei Zhao-lian..Relationship between lower number of oocytes retrieved and clinical outcomes of in vitro fertilization-embryo transfer[J].生殖医学杂志,2012,21(z1):36-41,6.
