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基于响应曲面法的龙须藤多糖提取条件优化

蔡亮亮 余方荣 李西海 叶蕻芝 徐慧凤 刘献祥

天然产物研究与开发2012,Vol.24Issue(12):1837-1843,7.
天然产物研究与开发2012,Vol.24Issue(12):1837-1843,7.

基于响应曲面法的龙须藤多糖提取条件优化

Optimization of Extraction Conditions of Bauhinia championii Benth Polysaccharide based on Response Surface Methodology

蔡亮亮 1余方荣 1李西海 2叶蕻芝 2徐慧凤 2刘献祥2

作者信息

  • 1. 福建中医药大学药学院
  • 2. 福建中医药大学中西医结合研究院,福州350108
  • 折叠

摘要

Abstract

Response surface methodology was applied to optimize the main extraction conditions of Bauhinia championii Benth polysaccharides . The main influence factors was determined by single factor test and the results showed that optimum extraction conditions were as follows;the extraction temperature was 100 ℃ and extraction time was 4 h,the liquid-solid ratio was 23 and the extraction times was 2. These predicted values were also verified by validation experiments.

关键词

龙须藤/多糖/响应曲面法/Box-behnken设计

Key words

Bauhinia championii Benth/Polysaccharides/Response surface methodology/Box-Behnken design

分类

医药卫生

引用本文复制引用

蔡亮亮,余方荣,李西海,叶蕻芝,徐慧凤,刘献祥..基于响应曲面法的龙须藤多糖提取条件优化[J].天然产物研究与开发,2012,24(12):1837-1843,7.

基金项目

国家自然科学基金项目(81102609) (81102609)

福建省自然科学基金项目(2011J05074) (2011J05074)

陈可冀中西医结合发展基金(CKJ20110003) (CKJ20110003)

天然产物研究与开发

OA北大核心CSCDCSTPCD

1001-6880

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