同位素2012，Vol.25Issue(4)：214-218,5.
13C-甲醇的制备
Synthesis of 13C-labeled Methanol
摘要
Abstract
A novel convenient method for the synthesis of 13C-methanol was described. 13C-methanol was prepared by means of catalytic hydrogenation, and then as-synthesized methanol solution was further purified in a microscale high-efficient rectification column. The chemical purity of 13C-methanol was more than 99. 5%. The synthetic route was featured by mild conditions and high yields of more than 90% based on isotopic substrate consumed. The product was characterized by GC-MS and 1H NMR, and the 13C abundance of 13C-methanol was more than 97％. Compared with the raw materials, the reduction of relative isotopic abundance of product was less than 1%.关键词
13C标记/甲醇/催化加氢Key words
13C-label/ methanol/ catalytic hydrogenation分类
化学化工引用本文复制引用
罗勇,杜晓宁,宋家龙,陆平晔,李美华..13C-甲醇的制备[J].同位素,2012,25(4):214-218,5.基金项目
"十一五"国家科技支撑计划(2009BAK61B04) （2009BAK61B04）
科技部转制院所专项(2011EG116066) （2011EG116066）
