同位素2012，Vol.25Issue(4)：219-227,9.
D-半乳糖-1-13C的合成与表征
Synthesis and Characterization of D-Galactose-1-13C
摘要
Abstract
D-Galactose-1-13 C was synthesized with nitromethane-13 C as starting material. The separation was performed of the epimers of nitro-D-Galactitol and nitro-D-talitol, which resulted in D-Galactose being obtained and the resolution of the epimers of D-Galac-tose and D-taltose being avoidance. D-Galactose-1-13 C was characterized by HPLC-ELSD, LC-MS and 1H NMR. The fine structure and 13C abundance of it were done by LC-MS and 1H NMR. The yield of 13C-labeled D-Galactose was 42. 6% with 99. 1% 13C abundance, 100. 0% optical purity and 99. 7% chemical purity.关键词
D-半乳糖-1-13C/合成/13C标记Key words
D-Galactose-1-13C/ synthesis/ 13C-labeled分类
化学化工引用本文复制引用
卢伟京,吴开成,李帅,徐仲杰..D-半乳糖-1-13C的合成与表征[J].同位素,2012,25(4):219-227,9.基金项目
国家高技术研究发展计划项目(2008AA022427) （2008AA022427）
