无机材料学报2013，Vol.28Issue(1)：40-44,5.DOI:10.3724/SP.J.1077.2013.12038
致密羟基磷灰石球粒的制备及其生物学性能研究
Research on Preparation and Biological Properties of Dense Hydroxyapatite Spheres
摘要
Abstract
By using carboxy methyl chitosan (CMCS) and gelatin (Gel) as adhesive, the nano-HA slurry which was fabricated via a precipitation process as the raw material, dense HA spheres with a uniform size distribution and good geometry were prepared successfully by means of Sol-Gel method. Dense HA spheres with a porosity of 4.7% ±0.6% have a higher compressive strength (8.9 + 0.4) MPa than that of porous HA spheres (7.9 + 0.2) MPa with a porosity of 16.4%+0.5% (particles with diameter of 0.5 mm). The results of biomimetic mineralization and cell culture show that dense HA spheres have an excellent biological property.关键词
羟基磷灰石/溶胶-凝胶法/高强度/致密度/生物学性能Key words
hydroxyapatite/ Sol-Gel method/ high strength/ density/ biological property分类
医药卫生引用本文复制引用
罗会涛,智伟,鲁雄,李金雨,冯波,翁杰..致密羟基磷灰石球粒的制备及其生物学性能研究[J].无机材料学报,2013,28(1):40-44,5.基金项目
国家重大科学研究计划(2012CB933602) （2012CB933602）
国家自然科学基金(51172188) （51172188）
四川省科技支撑计划(2010FZ0048) （2010FZ0048）
