无机材料学报2013，Vol.28Issue(1)：74-78,5.DOI:10.3724/SP.J.1077.2013.12176
蜡球造孔法制备多孔HA陶瓷支架及其性能优化
Preparation and Optimization of Porous HA Ceramic Scaffolds by Wax Spheres Leaching Method
摘要
Abstract
Interconnectivity of tissue engineering scaffolds plays a very important role in biological performance in vivo. In this work, chitin sol and wax spheres were used for preparing porous hydroxyapatite (HA) ceramics scaffolds by particle leaching and gel-casting methods. Under the same mounded casting condition, the effect of ratio of slurry/wax pore former on porosity, shrinkage, interconnectivity, porous structure and compressive strength were investigated systematically. Porous HA ceramic scaffolds were evaluated by gravimetric method, stereomicroscope, X-ray diffraction (XRD), scanning electron microscope (SEM) and universal testing machine. The results show that the present method is an effective method to fabricate a highly porous HA ceramic scaffolds. With increasing the ratio of slurry/wax spheres, the interconnectivity gets better and the optimal ratio of slurry/wax spheres is 1:1.2.关键词
多孔HA陶瓷支架/蜡球堆积/贯通性/抗压强度Key words
porous HA ceramic scaffolds/ accumulated wax spheres/ interconnectivity/ compressive strength分类
医药卫生引用本文复制引用
赵婧,李金雨,智伟,鲁雄,贾治彬,翁杰..蜡球造孔法制备多孔HA陶瓷支架及其性能优化[J].无机材料学报,2013,28(1):74-78,5.基金项目
国家重大科学研究计划(2012CB933602) （2012CB933602）
国家自然科学基金(51205327,51172188) （51205327,51172188）
中央高校基本科研业务费专项资金(A0920502051113-95) （A0920502051113-95）
四川省青年科技基金创新团队项目(2010JQ0081) （2010JQ0081）
