武警医学2013，Vol.24Issue(1)：37-40,4.
ER、PR在绝经期子宫及子宫腺肌症中的表达
Level distribution of estrogen receptor and progesterone receptor in human uterus of menopause and adenomyosis group
摘要
Abstract
To compare the gradient distribution of estrogen and progesterone receptor in the whole layers of the u-terus (mucous, superficial myometrium, deep myometrium layer and subserious layers) by the expression of estrogen and progesterone receptors. Methods To evaluate the distribution and intensity of estrogen receptor (ER) and progesterone receptor (PR) stained in the various part of human endometrium and myometrium, two different diseases were chosen in the menopause and adenomyosis group. Immuno - histochemical study was performed on ER and PR in the whole layers (mucous layer, superficial myometrium layer, and deep myometrium layer). Results There was significant difference in distribution of ER and PR between endometrium and other layers ( P < 0. 01) in menopause group. There was significant difference in distribution of ER and PR between subserous and other layers (P = 0.000) in adenomyosis group. Conclusions In menopause ER and PR levels is maximum in the endometrium. So the endome-trial abalation is effective for the tamoxifen - treated breast cancer patients.关键词
雌激素受体/孕激素受体/他莫昔芬/子宫腺肌症Key words
estrogen receptor/progesterone receptor/tamoxifen/adenomyosis分类
医药卫生引用本文复制引用
李靖,冯力民,刘晖..ER、PR在绝经期子宫及子宫腺肌症中的表达[J].武警医学,2013,24(1):37-40,4.
