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食管胃结合部癌根治术后早期复发相关因素分析

王国栋 武爱文 程晓静 邢晓芳 张连海 季加孚

外科理论与实践2013,Vol.18Issue(1):21-24,4.
外科理论与实践2013,Vol.18Issue(1):21-24,4.DOI:10.3969/j.issn.1007-9610.2013.01.007

食管胃结合部癌根治术后早期复发相关因素分析

Risk factors associated with early recurrence of adenocarcinoma of esophagogastric junction after curative resection

王国栋 1武爱文 1程晓静 1邢晓芳 1张连海 1季加孚1

作者信息

  • 1. 北京大学肿瘤医院胃肠外科,北京100142
  • 折叠

摘要

Abstract

Objective To investigate the elinicopathological factors associated with early recurrence of adenocarcinoma of esophagogastric junction after curative resection. Methods We reviewed clinical data of patients with adenocarcinoma of esophagogastric junction who underwent RO resection from Dec 1995 to Dec 2007. Risk factors were retrospectively analyzed hyx2 test and logistic multiple regression. Results The mean time to tumor recurrence is (16.3±1.2) months after RO resection. The calculated 1-year-recurrence is 76.6%. Univariate analysis showed that the histological grade, number of positive lymph nodes and vascular invasion were related with the tumor recurrence time (P<0.05). Multi-variate Logistic multiple regression analysis showed that histologic grade and vascular invasion were independently related with early tumor recurrence (P <0.05). Conclusions Histological grade and vascular invasion are significant and independent factors for predicting the tumor recurrence of adenocarcinoma of esophagogastric junction after RO resection.

关键词

食管胃结合部癌/肿瘤复发/危险因素/回归分析

Key words

Adenocarcinoma of esophagogastric junction/ Neoplasm recurrence/ Risk factor/ Regression analysis

分类

医药卫生

引用本文复制引用

王国栋,武爱文,程晓静,邢晓芳,张连海,季加孚..食管胃结合部癌根治术后早期复发相关因素分析[J].外科理论与实践,2013,18(1):21-24,4.

基金项目

国家自然科学基金(81071983) (81071983)

外科理论与实践

OACSTPCD

1007-9610

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