外科理论与实践2013，Vol.18Issue(1)：77-80,4.DOI:10.3969/j.issn.1007-9610.2013.01.019
空芯针活检漏诊乳腺导管原位癌伴浸润的危险因素分析
Analysis of risk factors associated with upstaging in patients with pre-operative diagnosis of ductal carcinoma in situ of breast by core needle biopsy
张熙 1陈小松 1吴佳毅 1黄欧 1何建蓉 1朱丽 1陈伟国 1李亚芬 1沈坤炜1
作者信息
- 1. 上海交通大学医学院附属瑞金医院乳腺疾病诊治中心,上海200025
- 折叠
摘要
Abstract
To estimate the post-operative diagnostic rate of ductal carcinoma in situ (DCIS) with invasion in patients diagnosed as DCIS pre-operatively via core needle biopsy (CNB) and to identify clinicopathological factors related with the upstaging. Methods Data were retrospectively collected from 52 cases with the preoperative diagnosis of DCIS who were treated in our hospital during 2009 Oct to 2012 Feb. The upstaging rate from DCIS to DCIS with invasion included breast cancer was calculated and the associated risk factors were also analyzed. Results The upstaging rate was 50%. It was showed by univariate and multivariate analysis that mass as main presentation (OR =6.4, 95%C7:1.2-35.2,P=0.032), clinical tumor size≥5 cm (OR=13.0, 95%C/: 1.2-137.9, P=0.033) were related with the postoperative diagnosis of DCIS with invasion. Conclusions Patients with the preoperative diagnosis of DCIS might have the possibility of being underestimated. Mass as main presentation and clinical tumor size≥5 cm were the factors associated with higher risk for invasive carcinoma. Further prospective cohort study is awaited to confirm our result. 关键词
乳腺导管原位癌/空芯针穿刺/浸润Key words
Ductal carcinoma in situ/ Core needle biopsy/ Invasion分类
医药卫生引用本文复制引用
张熙,陈小松,吴佳毅,黄欧,何建蓉,朱丽,陈伟国,李亚芬,沈坤炜..空芯针活检漏诊乳腺导管原位癌伴浸润的危险因素分析[J].外科理论与实践,2013,18(1):77-80,4.
