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小剂量阿司匹林肠溶片释放度的在线过程分析

马金刚 薛嵘 刘娜 王翔 赵兴红

西北国防医学杂志2013,Vol.34Issue(1):45-47,3.
西北国防医学杂志2013,Vol.34Issue(1):45-47,3.

小剂量阿司匹林肠溶片释放度的在线过程分析

On-line-fiber optic dissolution test of low-dose aspirin enteric-coated tablets

马金刚 1薛嵘 2刘娜 1王翔 1赵兴红1

作者信息

  • 1. 兰州军区联勤部药品仪器检验所,甘肃兰州730050
  • 2. 甘肃省人民医院肾内科
  • 折叠

摘要

Abstract

Objective: To study a method which can monitor the dissolution of aspirin enteric - coated tablets in vitro and real time. Methods: Fiber optic dissolution test system (FODT) was used to monitor the whole releasing procedure of aspirin enteric - coated tablets, the result was compared with that of Ch. P dissolution test ( Ch. P). Results; Fiber optic dissolution test system can monitor the whole drug releasing procedure, meanwhile showing complete drug stripping curve. Conclusion: No matter using fiber optic dissolution test system or using Ch. P, the determined result is no difference, and both of them can monitor the release of aspirin efficiently in vitro.

关键词

阿司匹林肠溶片/光纤药物溶出度实时测定仪/释放度

Key words

Aspirin enteric -coated tablets/ Fiber optic real time dissolution test system (FODTS) / Release

分类

医药卫生

引用本文复制引用

马金刚,薛嵘,刘娜,王翔,赵兴红..小剂量阿司匹林肠溶片释放度的在线过程分析[J].西北国防医学杂志,2013,34(1):45-47,3.

西北国防医学杂志

OACSTPCD

1007-8622

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