摘要
Abstract
Objective To observe the efficacy and safety of enteral nutrition suspension ( total protein fiber fruto -oligosaccharide, TPF - FOS )in the early enteral nutrition! EN treatment of patients with severe chest trauma. Methods From January 2010 to January 2012,48 patients with severe chest trauma were randomly divided into observation group and control group. The observation group began to receive the EN treatment within 48 hours after the admission to ICU( receiving TPF - FOS via nasogastric feeding tube ),while the control group began to receive the EN treatment 48 hours after the admission to ICU. A targeted content of 125. 52 J( 30 kcal )/( kg ? d )was given at least for 3 days. Observation was made in the level of serum proteins, the incidence of gastrointestinal adverse reactions,the time of mechanical ventilation,and the average length of stay in ICU,etc,on day 1 ,3 ,5 ,7 and 10 after admission to ICU. And the adverse events were recorded. Results On day 7 and 10 after the early EN support,the levels of serum prealbumin in the observation group were better than those in the control group( P <0. 05 ). From day 1 to 10,there was no significant difference in the levels of seralbumin and transferrin between the two groups. And there was no significant difference in the incidence of gastrointestinal reactions between the two groups, but the time of mechanical ventilation and the average length of stay in ICU in the observation group were all shorter than those in the control group( P <0. 05 ). Conclusion Early enteral nutrition with TPF - FOS via feeding tube in patients with severe chest trauma can make early recovery of serum prealbumin levels, improve the patients' nutrition status,and shorten the time of mechanical ventilation and length of stay in ICU.
关键词
重症胸部创伤/肠内营养/营养混悬液/血清蛋白Key words
severe chest trauma/ enteral nutrition/ enteral nutrition suspension/ serum protein分类
医药卫生
