疑难病杂志2013，Vol.12Issue(1)：10-12,3.DOI:10.3969/j.issn.1671-6450.2013.01.004
巴替非班在急性冠脉综合征患者经皮冠状动脉介入治疗中的应用价值
The effects of batifiban during percutaneous coronary intervention in acute coronary syndrome patients
摘要
Abstract
Objective To observe the clinical effect and safety of batifiban in non-ST segment elevation acute coro-nary syndrome ( ACS ) patients who received percutaneous coronary intervention ( PCI ). Methods A total of 66 non-ST seg-ment elevation ACS patients receiving PCI were included and randomized into batifiban group ( n = 34 ) and placebo group ( n = 32 ). There were 5 and 8 missing/excluded patients in group batifiban and placebo, respectively. The major adverse cardiac events( MACE) include refractory ischemia, new myocardial infarction and death, cerebral apoplexy and hemorrhage complication were observed. Results The baseline data of the two groups were not significantly different ( P > 0. 05 ). The MACE at 30 days was not significantly different between two groups ( P >0.05 ). There were no differences in the incidence of bleeding or platelet decrease between two groups. There was no coronary slow flow phenomenon in two groups. Conclusion Compared with placebo group, using batifiban in non-ST segment elevation ACS patients is safe and effect during PCI proce-dures.关键词
急性冠脉综合征,非ST段抬高/巴替非班/经皮冠状动脉介入术Key words
Acute coronary syndrome,non-ST segment elevation/Batifiban/Percutaneous coronary intervention引用本文复制引用
黄觊,钱海燕,李志忠,张京梅,王茜,陶英..巴替非班在急性冠脉综合征患者经皮冠状动脉介入治疗中的应用价值[J].疑难病杂志,2013,12(1):10-12,3.基金项目
国家自然科学基金(No.81000130,81000091),北京市卫生局青年科学研究资助项目(No.QN2010-010) （No.81000130,81000091）
