医药导报2013，Vol.32Issue(1)：100-105,6.DOI:10.3870/yydb.2013.01.036
复方丹参滴丸治疗冠心病心绞痛的有效性和安全性系统评价
Systematic Evaluation of Efficacy and Safety of Compound Salvia Droplet Pills for Angina Pectoris
摘要
Abstract
Objective To evaluate the efficacy and safety of Compound Salvia Droplet Pills (CSDP) for treating angina pectoris.Methods Foreign database ( Cochrane Library online edition) and Chinese database ( Chinese Biomedical Database, China Academic Journal Full-text Database of Chinese Scientific Journals, and Wanfang Digital Journal Full-text Database) were retrieved via internet, according to Cochrane systematic review method of quality evaluation.Meta-analysis of homogeneous studies was carried out with RevMan 5.0, and descriptive qualitative analysis was performed for the data could not be merged.Results The results showed that CSDP alleviated the onset of angina pectoris ( OR = 2.18, 95% CI [ 1.75,2.70 ],P<0.000 01),improved ischemic ECG(OR = 2.39,95%CI [1.99,2.88] ,P<0.000 01), lowered cholesterol( WMD= 1.31, 95% CI [1.03, 1.58],P<0.000 01) and triacylglycerol ( WMD = 2.05, 95% CI [ 1.65 ,2.45 ] ,P<0.000 01), and raised the heart rate variability, and presented no obvious side effects.Conclusion CSDP demonstrated curative effect on angina pectoris, and no obvious side effects, which suggest that CSDP are effective and safe for treating angina pectoris.关键词
丹参滴丸,复方/冠心病心绞痛/有效性/安全性/系统评价Key words
Salvia Droplet Pills,compound/Angina pectoris/Efficacy/Safety/Systematic evaluation分类
医药卫生引用本文复制引用
叶太生,张莹雯,胡汉昆..复方丹参滴丸治疗冠心病心绞痛的有效性和安全性系统评价[J].医药导报,2013,32(1):100-105,6.基金项目
国家科技支撑计划课题(2009BAI76B030226) （2009BAI76B030226）
