湖北医药学院学报2012，Vol.31Issue(2)：153-156,4.
肾髓质癌临床病理特征
Clinicopathological Analysis of Renal Medullary Carcinoma
罗晓青 1向自武 1周晓红 1曹进 1郭永连2
作者信息
- 1. 湖北医药学院附属襄阳医院病理科,湖北襄阳441000
- 2. 湖北医药学院附属襄阳医院泌尿外科,湖北襄阳441000
- 折叠
摘要
Abstract
Objective To analyze the clinicopathological,and molecular biology characteristics of the renal medullary carci-noma(MC) ,to improve the level of the diagnosis and treatment of the disease. Methods A retrospective study was performed in one case of MC. Referring to the latest domestic and foreign literature,the clinical,pathological,and molecular biology characteristics were analyzed. Results MC occurs most in the children and young adults. Histologically, it has high grade tumor cells with eosinophilic cytoplasm,vacuolar nucleus and prominent nuclei, forming yalk sac like,reticular,mi-crocystic, solid sheet arrangements. Stromal fibrous proliferation with infiltration of neutrophils and eosinophils was also seen. Immunohistochemically,the tumor cells were positive for CK,Vim,and EMA, focal positive for CK7,negative for HM-WCK(34βE12),which helps to distinguish with the renal collecting duct carcinoma. Conclusion Renal medullary carcinoma is an extremely rare aggressive and malignant tumor with characteristics of high grade tumor cells and diversity arrangement, needs to distinguish with the renal collecting duct carcinoma and Rhabdoid tumor. Early diagnosis and treatment is the key to improve its efficacy.关键词
肾髓质癌/病理形态学/免疫组织化学Key words
Renal medullary carcinoma /Pathomorphology/Immunohistochemistry分类
医药卫生引用本文复制引用
罗晓青,向自武,周晓红,曹进,郭永连..肾髓质癌临床病理特征[J].湖北医药学院学报,2012,31(2):153-156,4.
