中国肺癌杂志2013，Vol.16Issue(2)：97-101,5.DOI:10.3779/j.issn.1009-3419.2013.02.07
EML4-ALK融合基因在非小细胞肺癌中的临床意义
Clinical Meaning of EML4-ALK Fusion Gene in Non-small Cell Lung Cancer
韩卫1
作者信息
- 1. 233000蚌埠,蚌埠医学院第一附属医院肿瘤内科
- 折叠
摘要
Abstract
Lung cancer continues to be the leading cause of cancer death worldwide, and non-small cell lung cancer (NSCLC) is the most common type of lung cancer. Molecular targeted therapy is the most promising development part in the treatment of NSCLC. In recent years, more and more attention has been focused on some new molecular targets in NSCLC, such as echinodem microtubule-associated protein-like4/anaplastic lymphoma kinase (EML4-ALK) fusion gene. This review will focus on the basic structure, dinicopathologic features, detection method, ALK inhibitor and therapeutic meaning of EML4-ALK in NSCLC.关键词
肺肿瘤/EML4-ALK融合基因/分子靶向治疗Key words
Lung neoplasms/ EML4-ALK/ Molecular targeted therapy分类
医药卫生引用本文复制引用
韩卫..EML4-ALK融合基因在非小细胞肺癌中的临床意义[J].中国肺癌杂志,2013,16(2):97-101,5.
