摘要
Abstract
Objective To investigate the risk factors for hospital-acquired lower respiratory tract infection(LRTI) in an intensive care unit (ICU) , so as to provide reference for making effective measures for controlling healthcare-associated infection (HAD. Methods A retrospective analysis was conducted on medical records of 1 062 fCU patients who were admitted in fCU from December 2008 to December 2010, patients' hopitalization time was >48 hours, ages were ≥18 years old, 68 patients who were confirmed LRT1 was as case group; by 1:2 matched cases of same gender, same age group, and same admission time, 136 patients without HA1 was as control group, risk factors for LRT1 were analysed. Results Univariate analysis showed that length of stay in ICU≥15 days , incision of trachea, endotracheal intubation/mechanical ventilation, use of antimicrobial agents >2 types and duration >2 weeks, aerosol inhalation were risk factors of LRT1 in fCU patients; Multivariate Logistic regression analysis on 9 screened risk factors showed that length of stay in fCU ≥15 days (OR 95% CI, 1. 153 - 4. 912) , incision of trachea (OR 95% CI, 1. 836 - 9. 967) , endotracheal intubation/mechanical ventilation (OR 95% CI, 1. 163 - 5. 774) , use of antimicrobial agents >2 types and duration >2 weeks (OR 95% CI, 1. 016 - 5. 813) were independent risk factors for LRTI. Conclusion Multiple factors contribute to the occurrence of LRT1 in fCU patients, comprehensive preventive treatment based on the risk factors is helpful for reducing HAL.关键词
重症监护室/医院感染/下呼吸道感染/危险因素Key words
intensive care unit/healthcare-associated infection/ lower respiratory tract infection/ risk factor分类
医药卫生
