中国内镜杂志2012，Vol.18Issue(11)：1174-1177,4.
内镜黏膜切除术治疗早期大肠癌60例及随访观察
Endoscopic mucosal resection of early colorectal cancer: a report of sixty cases and its follow-up
刘晓岗 1李易 1阳运超 1张仁翼 1李良平1
作者信息
- 1. 四川省人民医院 消化内科,四川成都610072
- 折叠
摘要
Abstract
[Objective] To analyze the safety, curative effect and prognosis of early colorectal cancer(ECC) treated by endoscopic mucosal resection (EMR) retrospectively. [ Methods ] A total of 60 cases of early colorectal cancer initially treated by EMR or endoscopic piecemeal mucosal resection (EPMR) by means of injection were enrolled. Endoscopic techniques, complications, post-EMR pathological diagnosis, subsequent surgical resection and corresponding pathology were recorded, endoscopic follow-up was included too. [Result] Of the 60 patients, En bloc resection was performed in 71.66%(43/60) of cases, but the complete resection rate was 91.67% (55/60) based on endoscopic and surgical pathology. The complications were as follows: 24 cases (40%) of hemorrhage during EMR procedure were cured by APC or metal clip. Delayed hemorrhage within the first week after EMR occurred in 2 cases (3.33%) and healed by endoscopic means. No perforation occurred. The post-EMR pathological findings showed 54 cases of intramucosal cancer and 6 cases of submucosal cancer. Five patients with intramucosal cancer underwent subsequent surgical resection, no residual cancer found in surgical specimen, but one case with positive endoscopic resection margin had lymph node metastasis. Five cases of submucosal cancer also underwent subsequent surgical resection, 2 of sml cases and 1 sm3 case without lymph node metastasis, but 2 of sm2 cases accompined by lymph node metastasis. The other 49 cases of intramueosal cancer and one case of sml cancer who denied surgical intervention were enrolled for endoscopic follow-up, no recurrent lesion or metastasis was revealed during the following period of from one to fifty months. [ Conclusion ] EMR is a safe endoscopic therapy for the treatment of early col-orectal cancer , its curative effect strictly depends on endoscopic techniques, post-EMR pathological assessment and meticulous endoscopic follow up.关键词
内镜黏膜切除术/早期大肠癌/随访Key words
endoscopic mucosal resection/ early colorectal cancer/ follow-up分类
医药卫生引用本文复制引用
刘晓岗,李易,阳运超,张仁翼,李良平..内镜黏膜切除术治疗早期大肠癌60例及随访观察[J].中国内镜杂志,2012,18(11):1174-1177,4.
