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热休克蛋白70保护肝缺血再灌注损伤的研究进展

韩效帆

中国普通外科杂志2013,Vol.22Issue(1):98-103,6.
中国普通外科杂志2013,Vol.22Issue(1):98-103,6.DOI:10.7659/j.issn.1005-6947.2013.01.023

热休克蛋白70保护肝缺血再灌注损伤的研究进展

Role of HSP7O in hepatic ischemia-reperfusion injury:recent progress

韩效帆1

作者信息

  • 1. 扬州大学附属第二临床医院 普通外科研究室,江苏扬州225002
  • 折叠

摘要

Abstract

Hepatic ischemia-reperfusion (IR) injury is a major cause of liver damage, and has become a hot and difficult field of study. Recent investigations reveal that heat shock protein 70 (HSP70) plays a critical role in protection of tissues and organs against IR injury. This paper overviews the actions of HSP70 in liver IR injury, which puts a special emphasis on the mechanisms underlying its protective effect such as regulation of inflammation factors, and anti-apoptotic and antioxidative effect.

关键词

再灌注损伤,肝/HSP70热休克蛋白质类/综述文献

Key words

Reperfusion Injury, Liver/ HSP70 Heat-Shock Proteins/ Review

分类

医药卫生

引用本文复制引用

韩效帆..热休克蛋白70保护肝缺血再灌注损伤的研究进展[J].中国普通外科杂志,2013,22(1):98-103,6.

基金项目

江苏省扬州市社会发展科技攻关项目基金资助项目(YZ2010087). (YZ2010087)

中国普通外科杂志

OA北大核心CSCDCSTPCD

1005-6947

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