中国全科医学2012，Vol.15Issue(31)：3606-3609,4.DOI:10.3969/j.issn.1007-9572.2012.11.013
高血压前期体检人群体质指数对24 h动态血压监测血压水平的影响研究
Effect of Body Mass Index on Parameters of Ambulatory Blood Pressure Monitoring in Population with Pre-hypertension Examination
摘要
Abstract
Objective To investigate relationship between body mass index (BMI) and parameters from ambulatory blood pressure monitoring in population who underwent pre - hypertension examination. Methods Totally 243 persons who underwent pre - hypertension examination form January 2007 to December 2011 in our physical examination center were recruited. They were divided based on their BMI as normal group (18. 5 kg/m2 ≤BMI <24. 0 kg/m2) , overweight group (24. 0 kg/m2≤ BMI <28. 0 kg/m2) and obesity group (BMI≥28. 0 kg/m2) . The parameters of blood sugar, creatine ( Cr) , total cholesterol (TC) , triglyceride ( TG) , high - density lipoprotein cholesterol ( HDL - C) and low - density lipoprotein cholesterol ( LDL -C) were assyed by Hitachi 7600 - 120 automatic biochemistry analyzer. The body height and BMI were measured by SECA height and BMI meter, BMI = weight ( kg) /height2 ( m2 ). The blood pressure at setting position was taken by Standard mercury sphygmomanometer 15 min after rest in daytime. The ambulatory blood pressure monitoring was conducted by using Accuwin 2. 0 of Merrill Lynch. Results Among the three groups there were no significant differences in BMI, blood sugar, TG and HDL - C ( P < 0. 01) , but there were in Cr, TC, LDL - C ( P > 0. 05 ) . And there were significant differences in 24 h average diagnostic blood pressure, average diagnostic blood pressure in daytime and at night, standard deviation of daytime diagnostic blood pressure , loads of daytime and night diagnostic blood pressure ( P < 0. 05 ) ; but no significant difference was found in 24 h average systolic blood pressure, systolic blood pressure in daytime and at night, standard deviations of daytime and night systolic blood pressure, standard deviation of night diagnostic blood pressure, and loads of daytime and night systolic blood pressure ( P > 0. 05). Pearson correlation analysis showed that the BMI was positively correlated with the 24 h average systolic and diagnostic blood pressure (r =0. 128, r =0. 188) , daytime average systolic and diastolic blood pressure (r =0. 154, r =0. 186) , night average diagnostic blood pressure (r =0. 148) , loads of daytime systolic and diastolic blood pressure (r = 0. 126, r =0. 146) , and standard deviations of daytime and night (r =0.253, r =0.190) (P<0. 05). After regulating age, sex, smoking, alcohol drinking, blood sugar, Cr, TC, TG, HDL - C and LDL -C, the multiple linear regression analysis showed that the BMI was still correlated with 24 h average diagnostic blood pressure, daytime average diagnostic blood pressure, standard deviations of daytime and night diagnostic blood pressure independently. Conclusion The ambulatory blood pressure monitoring indicates that the overweight and obesity may obviously increase blood pressure level, blood pressure load and blood pressure variability in population with pre - hypertension examination. This population can prevent the onset of hypertension through improving dietary structure, enhancing physical exercise, and reducing body mass.关键词
人体质量指数/高血压/血压监测,便携式/高血压前期Key words
Body mass index/ Hypertension/ Blood pressure monitoring, ambulatory/ Prehypertension分类
医药卫生引用本文复制引用
李曦,胡荣,芦燕玲,于利群,周生来..高血压前期体检人群体质指数对24 h动态血压监测血压水平的影响研究[J].中国全科医学,2012,15(31):3606-3609,4.基金项目
十一五国家科技支撑计划基金项目(2008BAI52B06) （2008BAI52B06）
