摘要
Abstract
Objective To observe the influence of postoperative application of enteral nutrition (EN) with accessory Bazhen Decoction on hospitalization days, tube feeding duration of enteral nutrition, nutritional support costs, hospitalization drug cost ratio and total hospitalization costs in patients with gastric cancer after operation. Methods In this prospective, randomly , single blinded, controlled clinical trial 88 patients with gastric cancer were randomly divided into three groups: control group ( parenteral nutrition, PEN, n = 27 ) , study group A ( EN, n = 30) and study group B ( Bazhen Decoction and EN, n = 31). The patients in group A and B were given isocaloric and isonitrogonous enteral nutrition via naso - gastric tube, and those in group B were administered . additional Bazhen Decoction ( 100 ml) from the second post - operation day to the day without naso gastric tube. The patients in the control group were given isocaloric and isonitrogonous parenteral nutrition. The hospitalization days, tube feeding duration of enteral nutrition, nutritional support costs, hospitalization drug cost ratio and total hospitalization costs were observed for all the patients. Results The number of hospitalization days was ( 18 ±4) in group A and ( 17 ± 3 ) in group B, being less than ( 20 ± 5 ) in the control group ( P < 0. 05 ) , and the number in group B was less than that in group A ( P < 0. 05 ) . The number of tube feeding days of enteral nutrition was ( 14 ± 2 ) in group B, being less than (11 ± 2 ) in group A (P < 0. 05). The nutritional support cost was RMB (5 064 ± 362 ) yuan in group A and ( 4 725 ±311) in group B, being lower than (5 639 ±613) in the control group (P <0. 05) , and the cost in group B was less than that in group A (P < 0. 05 ) . The hospitalization drug cost ration was (51 ±7)% in group A and (42 ± 7 ) % in group B, being lower than (61 ± 6 ) % in the control group ( P < 0. 05 ) , and the cost ratio in group B was less than that in group A ( P < 0. 05 ) . The total hospitalization cost was RMB (42 071 ±5 600) in group A and (33 904 ±5 758) in group B, being significantly lower that (47 984 ± 7 004 ) yuan in the control group ( P < 0. 05 ) , and the cost in group B was less than that in group A ( P < 0. 05 ) . Conclusion The enteral nutrition (EN) with accessory Bazhen Decoction can positively improve the cellular immune function and nutritional status in patients with gastric cancer after operation, and can also reduce the hospitalization days and the tube feeding duration of enteral nutrition, decrease the nutritional support costs, hospitalization drug cost ratio and total hospitalization costs. Thereby it has a positive significance in economics.关键词
胃肿瘤/八珍汤/肠内营养/经济学意义Key words
Stomach neoplasms/ Bazhen decoction/ Enteral nutrition/ Economic significance分类
医药卫生
