中国全科医学2013，Vol.16Issue(1)：47-49,3.DOI:10.3969/j.issn.1007-9572.2013.01.014
慢性阻塞性肺疾病患者颈动脉弹性相关参数分析
Assay of Carotid Elasticity in Patients with Chronic Obstructive Pulmonary Disease
杨畅 1冯燕 2王新卫 1刘新年1
作者信息
- 1. 430030,湖北省武汉市,中山医院呼吸内科
- 2. 湖北省武汉市第六医院病理科
- 折叠
摘要
Abstract
Objective To determine relevant parameters of carotid elasticity in patients with chronic obstructive pulmonary disease ( COPD ) . Methods Totally 40 patients with COPD and 36 controls with normal pulmonary function were recruited. The clinical history was collected, and blood pressure, blood lipid, blood sugar and body mass index were measured for all the subjects. Parameters of carotid elasticity including beta stiffness index ( p ), arterial compliance ( AC ), augmentation index ( AI), and one point pulse wave velocity ( PWVp ) were determined by elastography tracking technique with ultrasound device. Results Compared with the controls, COPD patients had significantly higher parameters in p value [ ( 9. 06 ± 2. 05 ) vs. ( 7. 65 ± 2. 13 ) ], in PWVp [ ( 7. 05 ± 0. 81 ) m/s vs. ( 6. 22 ± 0. 90 ) m/s ], and in AI [ ( 27. 56 ± 9. 56 )% vs. ( 20. 01 ± 5. 56 )% ] ( P < 0. 05 ); and had significantly lower parameter in AC [ ( 0. 61 ± 0. 16 ) mmVkPa vs. ( 0. 78 ± 0. 15 ) mm2/kPa ] ( P < 0. 05 ). And compared with COPD patients at Ⅰ -Ⅱ stage, the COPD patients at Ⅲ- Ⅳ had higher parameters in p [ ( 9. 82 ±2. 76 ) vs. ( 8. 23 ± 1. 34 ) ] and PWVβ [ ( 0. 69 ±0. 08 ) m/s vs. ( 0. 55 ±0. 15 ) m/s ] ( P <0. 05 ). Conclusion The carotid arterial stiffness of patients with COPD increased, and it gets severer as the condition of COPD becomes more serous.关键词
肺疾病,慢性阻塞性/颈动脉/弹性参数Key words
Pulmonary disease, chronic obstructive/ Carotid artery/ Elastic parameter分类
医药卫生引用本文复制引用
杨畅,冯燕,王新卫,刘新年..慢性阻塞性肺疾病患者颈动脉弹性相关参数分析[J].中国全科医学,2013,16(1):47-49,3.
