中国全科医学2013，Vol.16Issue(1)：93-94,104,3.DOI:10.3969/j.issn.1007-9572.2013.01.029
医院与社区获得性耐甲氧西林金黄色葡萄球菌感染的临床特点和耐药性的对比分析
Clinical Features and Antimicrobial Resistance of Hospital- and Community-acquired MRSA Infection
摘要
Abstract
Objective To investigate the clinical features and antimicrobial resistance of hospital - and community -acquired MRSA infections. Methods The MRSA infection cases in our hospital between May 2010 and April 2011 were retrospectively analyzed. Results Of 183 MRSA infections, 152 ( 83. 1% ) were hospital - acquired MRSA ( HA - MRSA ) infections and 31 ( 16. 9% ) were community - acquired MRSA ( CA - MRSA ) infections. The proportion of patients aged 60 years old and above accounted for 67. 8% ( 103 ) of the patients with HA - MRSA, higher than that ( 19. 4% , 6 ) of the patients with CA - MRSA (χ2 = 25. 05, P < 0. 001 ). Patients with HA - MRSA mainly came from Department of Neurology ( 17. 8% , 27/152 ) and ICU ( 15. 8% , 24/152 ), while patients with CA - MRSA mainly came from Department of Dermatology ( 19. 4% , 6/31 ) and Emergency ( 19.4% , 6/31 ). HA -MRSA infections had higher resistance rate to moxifloxacin, levofloxacin, gentamicin, rifampicin, and tetracycline than CA - MRSA infections ( P <0. 05 ). Conclusion HA - MRSA infections were common in elderly patients most of whom had serious co - morbidities. Among these co - morbidities, cerebral vascular diseases were most commonly seen. The cases of HA - MRSA infections mainly came from Departments of Neurology, Neural Surgery and ICU. The samples mainly consisted of sputum and blood. CA - MRSA infections were common in otherwise healthy young people from Departments of Dermatology, Emergency, and Respiratory Diseases. They often showed up as skin infection or severe pneumoni-a. Different clinical features of HA - MRSA and CA - MRSA infections can assist in the differentiation between the two once MRSA is detected from laboratory tests. Drug susceptibility test can further help the clinicians to choose appropriate antimicrobial drugs.关键词
耐甲氧西林金黄色葡萄球菌/医院感染/社区获得性感染Key words
Methicillin -resistant staphylococcus aureus/ Hospital infection/ Community associated infection分类
医药卫生引用本文复制引用
陈迎晓,黄瑜,王晓东,李庆兴,王邦松..医院与社区获得性耐甲氧西林金黄色葡萄球菌感染的临床特点和耐药性的对比分析[J].中国全科医学,2013,16(1):93-94,104,3.基金项目
温州市科技局项目(Y20090382) （Y20090382）
