中国全科医学2013，Vol.16Issue(2)：120-122,3.DOI:10.3969/j.issn.1007-9572.2013.01.038
老年男性非酒精性脂肪性肝病相关因素研究
Risk Facters of Non-alcoholic Fatty Liver Disease in Elderly Men
游志清 1邢军 1张蜀平 2郭蔚 1程莹 1郎红梅 1郝新忠 3万勇 1李宁娜 1艾智华1
作者信息
- 1. 610083,四川省成都市,成都军区总医院内分泌科
- 2. 610083,四川省成都市,成都军区总医院干部病房高诊室
- 3. 610083,四川省成都市,成都军区总医院地方干部病房
- 折叠
摘要
Abstract
Objective To investigate the risk factors of noil - alcoholic fatty liver disease ( NAFLD ) in elderly men. Methods Among 1 043 elderly ( 360 years ) men who received health check - up in our hospital from April to August 2011 , 242 were diagnosed with fatty liver by abdominal ultrasound, of which 164 were NAFLD ( NAFLD group ). Another 72 healthy subjects were randomly selected as the control group. The clinical features and laboratory findings were compared between two groups. The potential risk factors of NAFLD were analyzed by non - conditional Logistic stepwise regression analysis. Results The levels of total cholesterol, high - density lipoprotein, apo Al , apo B, and white blood cell were not significantly different between these two groups ( P > 0. 05 ), whereas the body mass index ( BMI ), systolic blood pressure, diastolic blood pressure, fasting plasma glucose ( FBG ) and triglycerides showed significant differences ( P < 0. 01 ). The prevalences of obesity/overweight, hypertension, hypertriglyceridemia, and hyperglycemia were also significantly different between these two groups ( P < 0.01 ). Non - conditional logistic stepwise regression analysis showed that BMI [ OR = 1.449, 95% CI ( 1.237, 1. 697), P = 0. 000 ], FBG [ OR = 2.188, 95%C/(1.353, 3.537), P = 0. 001]. and triglyceride [ OR = 2. 213 , 95%CI(1.353, 3. 621 ), P = 0. 002 ] were the risk factors of NAFLD. Conclusion The main risk factors of NAFLD include hypertriglyceridemia , hyperglycemia and obesity/overweight. Lowering plasma lipids and plasma glucose and weight loss by adopting healthy lifestyle are critical in the prevention and treatment of NAFLD.关键词
非酒精性脂肪肝/危险因素/老年人/男性Key words
Non - alcoholic fatty liver/Risk factors/Aged/Men分类
医药卫生引用本文复制引用
游志清,邢军,张蜀平,郭蔚,程莹,郎红梅,郝新忠,万勇,李宁娜,艾智华..老年男性非酒精性脂肪性肝病相关因素研究[J].中国全科医学,2013,16(2):120-122,3.
