中国全科医学2013，Vol.16Issue(2)：144-146,3.DOI:10.3969/j.issn.1007-9572.2013.01.045
急性ST段抬高型心肌梗死患者心型脂肪酸结合蛋白水平与GRACE危险评分的相关性研究
Relationship between Heart-type Fatty Acid-binding Protein and GRACE Risk Score in Patients with Acute ST-elevation Myocardial Infarction
摘要
Abstract
Objective To study the relationship between heart - type fatty acid - binding protein ( H - FABP ) level and Global Registry of Acute Coronary Events ( GRACE ) risk score in patients with acute ST - elevation myocardial infarction ( STEMI ). Methods From April 2010 to December 2011 , 60 STEM patients admitted to our hospital within 2 hours of symptom onset were enrolled in this study. Twelve hours after admission, blood samples were obtained for H - FABP measurement every two hours. Then, H - FABP peak values were found. The baseline data were recorded and the GRACE risk score were calculated. The Pearson's correlation analysis were used to analyze the relationship between the H - FABP peak value and GRACE risk score. Results The peak value of H - FABP was ( 59. 4 ± 23. 1 ) μg/L, which occmed 4~8 hours after admission. It was positively correlated with GRACE risk score in these patients ( r = 0.701 , P<0. 05 ). Conclusion H -FABP peak value is directly relevant with GRACE risk score in STEMI patients. Measurement of H - FABP level can provide additional risk stratification information in these patients.关键词
急性ST段抬高型心肌梗死/心型脂肪酸结合蛋白/全球急性冠状动脉事件注册危险评分Key words
Acute ST - elevation myocardial infarction/Heart - type fatty acid - binding protein/Global registry of分类
医药卫生引用本文复制引用
魏庆民,周彬,王晓纲,樊延明,王爱平,刘翠华..急性ST段抬高型心肌梗死患者心型脂肪酸结合蛋白水平与GRACE危险评分的相关性研究[J].中国全科医学,2013,16(2):144-146,3.基金项目
河北省科技支撑计划项目(11276103D-79) （11276103D-79）
