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糖化血红蛋白与急性心肌梗死患者经皮冠状动脉介入治疗后心功能的关系研究

王梅 王春梅 王成钢 艾辉 朱小玲

中国全科医学2013,Vol.16Issue(2):151-153,3.
中国全科医学2013,Vol.16Issue(2):151-153,3.DOI:10.3969/j.issn.1007-9572.2013.01.047

糖化血红蛋白与急性心肌梗死患者经皮冠状动脉介入治疗后心功能的关系研究

Relationship between HbA1c and Heart Function in Patients with Acute Myocardial Infarction Who Undergoing Primary Percutaneous Coronary Intervention

王梅 1王春梅 1王成钢 1艾辉 1朱小玲1

作者信息

  • 1. 100029北京市,首都医科大学附属北京安贞医院抢救中心
  • 折叠

摘要

Abstract

Objective To investigate the relationship between HbA1c, and heart function in patients with acute myocardial infarction ( AMI ) who undergoing primary percutaneous coronary intervention ( PCI ). Methods In 2009, 324 AMI patients undergoing primary PCI were enrolled in this study. According to the level of HhA,,., the patients were divided into high HhA,,. group ( HhA1c ≥6. 5% ) and control group ( HhA1c <6. 5% ), and the heart function were analyzed. Results Thrombol-ysis in myocardial infarction ( TIMI ) flow grade 0 was not significantly different between these two groups before PCI ( P > 0. 05 ). The number of injured blood vessels, reperfusion time of infarct - related artery ( IRA ), and no - flow phenomena were not significantly different ( P > 0. 05 ). The left ventricular ejection fraction ( LVEF ) and incidences of heart failure during hospital stay showed no significant differences ( P > 0. 05 ) but were significantly different three months after PCI ( P < 0. 05 ). As shown in multivariate analysis, after the other risk factors were adjusted, HbA1c ≥6. 5% was a predictor of heart failure three months after Pill [OR =2. 97%, 95% CI( 1.635, 5.018), P=0.021]. Conclusion The increased HhA1c level is a influencing factors of poor heart failure in AMI patients 3 month after PCI. HbA1c may be a useful indicator for the early intervetnion of AMI and blood sugar control.

关键词

急性心肌梗死/血管成形术,经腔,经皮冠状动脉/血红蛋白A,糖基化/心功能

Key words

Acute myocardial infarction/Angioplasty, transluminal, percutaneous coronary/Hemoglobin A, gly-cosylated/Heart function

分类

医药卫生

引用本文复制引用

王梅,王春梅,王成钢,艾辉,朱小玲..糖化血红蛋白与急性心肌梗死患者经皮冠状动脉介入治疗后心功能的关系研究[J].中国全科医学,2013,16(2):151-153,3.

中国全科医学

OA北大核心CSCDCSTPCD

1007-9572

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