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大肠埃希菌耐药性与抗菌药物使用量的相关性分析

展冠军 缪玉山 詹莹 厉伟兰

中国全科医学2013,Vol.16Issue(4):456-458,461,4.
中国全科医学2013,Vol.16Issue(4):456-458,461,4.DOI:10.3969/j.issn.1007-9572.2013.02.031

大肠埃希菌耐药性与抗菌药物使用量的相关性分析

Correlation between Antimicrobial Consumption and Resistance of Escherichia Coli

展冠军 1缪玉山 1詹莹 1厉伟兰1

作者信息

  • 1. 210009江苏省南京市,东南大学附属中大医院
  • 折叠

摘要

Abstract

Objective To explore the correlation between antimicrobial consumption and resistance of Escherichia coli. Methods The DDDs of 10 kinds of antimicrobials prescribed in our hospital during 2009 and 2011 were retrospectively studied. The DDDs were calculated every half year. The correlation of drug resistance rate of Escherichia coli with DDDs of 10 kinds of antimicrobials was analyzed using SPSS 18. 0 software. Results E coli maintained a low drug resistance only to IMI. E coli's resistance to TZP decreased greatly, and was moderately correlated with DDDs of CTR and AZM. E coli's resistance to TZP, CIP and LEV was correlated with DDDs of CAZ. E coli's resistance to CAZ, FEP and AZM was correlated with DDDs of FEP and CIP. E coli's resistance to TZP was correlated with DDDs of TZP and GEN. Drug resistance of E coli. was not correlated to other antimicrobials' DDDs. Conclusion Resistance rate of E coli is correlated with antimicrobials consumption, indicating proper use of antimicrobials to prevent or reduce bacterial resistance.

关键词

大肠埃希菌/耐药性/用药频度/相关性分析

Key words

Escherichia coli/ Drug resistance/ DDDs/ Correlation analysisc

分类

医药卫生

引用本文复制引用

展冠军,缪玉山,詹莹,厉伟兰..大肠埃希菌耐药性与抗菌药物使用量的相关性分析[J].中国全科医学,2013,16(4):456-458,461,4.

中国全科医学

OA北大核心CSCDCSTPCD

1007-9572

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