摘要
Abstract
Objective To explore the effectiveness of vitamin E combined with vitamin C in the intervention of carotid atherosclerotic plaques ( CAPs ). Methods A total of 196 45 - year - old - or - above patients with ultrasound - confirm CAPs ( and carotid intima media thickness≥ 1. 0 mm ) from 5 communities in Huangcun, Daxing District, Beijing, were enrolled. In addtion to routine aspirin and statin therapy, patients were further divided into four groups based on the administration of vitamins : group A ( supplemented with vitamin E, 200 mg/day ), group B ( supplenmented with vitamin E 200 mg, qn, and vitamin C 200 mg bid ), group C ( supplemented with vitamin C 200 mg bid ), and control group ( without any vitamin supplementation). After 18 months of treatment, the change in the size of CAPs were compared among these four groups. Results Compared with the control group, the size of CAPs in groups A, B, and C were not significantly different ( P >0. 05 ). The control group carotid atherosclerotic plaques difference before and after the intervention was statistically significant ( P < 0. 05 ); Group A, group B, the C group's differences were not statistically significant (P>0. 05). Conclusion Supplementation of vitamin C or E is not helpful to shrink CAPs.关键词
维生素E/维生素C/颈动脉粥样斑块/内膜中层厚度Key words
Vitamin E/ Vitamin C/ Carotid atherosclerotic plaques/ Intima media thickness分类
医药卫生
